Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 17/20 | 0.68 |
| ▸ | PPARA | Q07869 | 5/20 | 0.68 |
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5510036 | 0.92 | PPARD (0.64) | PPARDPPARAPPARG | |
| SCHEMBL5507593 | 0.90 | PPARD (0.59) | PPARDPPARAPPARGMAOBFFAR1 | |
| SCHEMBL5508433 | 0.89 | PPARD (0.76) | PPARDPPARAPPARG | |
| SCHEMBL5513320 | 0.83 | PPARD (0.52) | PPARDPPARAPPARG | |
| SCHEMBL5511791 | 0.82 | PPARD (0.79) | PPARDPPARAPPARGFFAR1FFAR4 | |
| SCHEMBL5510198 | 0.81 | PPARD (0.77) | PPARDPPARAPPARG | |
| SCHEMBL5507963 | 0.81 | PPARD (1.00) | PPARDPPARAPPARG | |
| SCHEMBL5512133 | 0.81 | PPARD (0.79) | PPARDPPARAPPARG | |
| SCHEMBL5513400 | 0.80 | PPARD (0.67) | PPARDPPARAPPARGMAOB | |
| SCHEMBL5512768 | 0.80 | PPARD (0.67) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39916-E1 | Compounds that modulate PPAR activity and methods for their preparation | WARNER LAMBERT COMPANY (US) | 2007-11-06 | — | — | US | disclosed |
| US-RE39916-E1 | Compounds that modulate PPAR activity and methods for their preparation | WARNER LAMBERT COMPANY (US) | 2007-11-06 | — | — | US | disclosed |
| US-RE39916-E1 | Compounds that modulate PPAR activity and methods for their preparation | WARNER LAMBERT COMPANY (US) | 2007-11-06 | — | — | US | disclosed |