Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.42 |
| ▸ | APP | P05067 | 4/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5515927 | 0.79 | ESR1 (0.40) | ESR1ESR2CYP17A1CYP3A4CYP11B1 | |
| SCHEMBL5518555 | 0.79 | ESR1 (0.45) | ESR1ESR2APPMEN1KMT2A | |
| SCHEMBL12912891 | 0.76 | ESR1 (0.46) | ESR1ESR2CYP17A1CYP3A4CYP11B1 | |
| SCHEMBL5511508 | 0.75 | ESR1 (0.39) | ESR1ESR2APPKDM4EMEN1 | |
| SCHEMBL5514088 | 0.75 | ESR1 (0.49) | ESR1ESR2CYP17A1CYP3A4CYP11B1 | |
| SCHEMBL5515809 | 0.74 | ESR1 (0.44) | ESR1ESR2APP | |
| SCHEMBL5512117 | 0.73 | ESR1 (0.49) | ESR1ESR2APPCYP3A4 | |
| SCHEMBL5514423 | 0.72 | ESR1 (0.46) | ESR1ESR2CYP17A1CYP3A4CYP11B1 | |
| SCHEMBL28692194 | 0.72 | ESR1 (0.46) | ESR1ESR2CYP17A1CYP3A4CYP11B1 | |
| SCHEMBL27639116 | 0.71 | ESR1 (0.54) | ESR1ESR2APPCYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208559-B2 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2007-04-24 | — | — | US | disclosed |
| US-20060135712-A1 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2006-06-22 | — | — | US | disclosed |