Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | F12 | P00748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5513548 | 0.79 | PLAU (0.44) | ESR1ESR2MEN1LMNAPOLB | |
| SCHEMBL30022727 | 0.79 | ESR1 (0.52) | ESR1ESR2CYP1A2MEN1LMNA | |
| SCHEMBL31633538 | 0.79 | CYP1A2 (0.43) | ESR1ESR2CYP1A2MEN1LMNA | |
| SCHEMBL7256843 | 0.79 | CYP1A2 (0.43) | ESR1ESR2CYP1A2MEN1LMNA | |
| SCHEMBL31633539 | 0.79 | CYP1A2 (0.43) | ESR1ESR2CYP1A2MEN1LMNA | |
| SCHEMBL5514174 | 0.79 | ESR1 (0.72) | ESR1ESR2CYP1A2 | |
| SCHEMBL7925571 | 0.79 | ESR1 (0.52) | ESR1ESR2CYP1A2MEN1LMNA | |
| SCHEMBL3822815 | 0.76 | ESR2 (0.49) | ESR1ESR2CYP1A2MEN1LMNA | |
| SCHEMBL31366695 | 0.76 | ESR2 (0.49) | ESR1ESR2CYP1A2MEN1LMNA | |
| SCHEMBL3171263 | 0.76 | MAPT (0.47) | ESR1ESR2MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100478364-C | Ethylene polymer and molded article obtained therefrom | MITSUI CHEMICALS INC (JP) | 2009-04-15 | — | — | CN | disclosed |
| US-7208559-B2 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2007-04-24 | — | — | US | disclosed |
| US-20060135712-A1 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2006-06-22 | — | — | US | disclosed |
| CN-1732189-A | Ethylene polymer and molded article obtained therefrom | MITSUI CHEMICALS INC (JP) | 2006-02-08 | — | — | CN | disclosed |