Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.69 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5510907 | 1.00 | TLR7 (0.69) | TLR7TLR8 | |
| SCHEMBL4528140 | 0.91 | TLR7 (0.66) | TLR7TLR8 | |
| SCHEMBL3861991 | 0.88 | TLR7 (0.69) | TLR7TLR8 | |
| SCHEMBL3861984 | 0.88 | TLR7 (0.69) | TLR7TLR8 | |
| SCHEMBL4528146 | 0.87 | TLR7 (0.68) | TLR7TLR8 | |
| SCHEMBL4528143 | 0.83 | TLR7 (0.68) | TLR7TLR8 | |
| SCHEMBL22559092 | 0.82 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL22558526 | 0.80 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL3861909 | 0.80 | TLR7 (0.77) | TLR7TLR8 | |
| SCHEMBL6246349 | 0.80 | TLR7 (0.73) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845988-A2 | SUBSTITUTED IMIDAZOQUINOLINES AND IMIDAZONAPHTHYRIDINES | 3M Innovative Properties Company (US) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006091394-A2 | SUBSTITUTED IMIDAZOQUINOLINES AND IMIDAZONAPHTHYRIDINES | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-08-31 | — | — | WO | disclosed |