SCHEMBL5511037

SCHEMBL5511037

C=CC(=O)NCCC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCNCC1

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EGFR P00533 20/20 0.68
KDR P35968 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4579725 0.91 EGFR (0.80) EGFRKDR
SCHEMBL5510867 0.90 EGFR (0.75) EGFRKDR
SCHEMBL5511536 0.89 EGFR (0.62) EGFRKDR
SCHEMBL4579864 0.82 EGFR (0.78) EGFRKDR
SCHEMBL4577855 0.81 EGFR (0.89) EGFRKDR
SCHEMBL5091125 0.81 EGFR (1.00) EGFRKDR
SCHEMBL4579045 0.81 EGFR (1.00) EGFRKDR
SCHEMBL4578968 0.81 EGFR (1.00) EGFRKDR
SCHEMBL4577754 0.80 EGFR (1.00) EGFRKDR
SCHEMBL4578874 0.80 EGFR (1.00) EGFRKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007055513-A1 QUINAZOLINE DERIVATIVES AS A SIGNAL TRANSDUCTION INHIBITOR AND METHOD FOR THE PREPARATION THEREOF HANMI PHARM. CO., LTD. (KR) 2007-05-18 WO disclosed