Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trifluoroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8764669 | 0.96 | — | — | |
| Trifluoroacetic Acid SCHEMBL4342494 | 0.92 | CA4 (0.38) | CA4CA2CA1CASP1FAHD1 | |
| Trifluoroacetic Acid SCHEMBL6912539 | 0.92 | CA4 (0.38) | CA4CA2CA1CASP1FAHD1 | |
| Trifluoroacetic Acid SCHEMBL2381055 | 0.92 | CA4 (0.38) | CA4CA2CA1CASP1FAHD1 | |
| Trifluoroacetic Acid SCHEMBL204190 | 0.92 | CA4 (0.38) | CA4CA2CA1CASP1FAHD1 | |
| Trifluoroacetic Acid SCHEMBL20569660 | 0.92 | CA4 (0.38) | CA4CA2CA1CASP1FAHD1 | |
| Trifluoroacetic Acid SCHEMBL20571141 | 0.92 | CA4 (0.38) | CA4CA2CA1CASP1FAHD1 | |
| Trifluoroacetic Acid SCHEMBL20569310 | 0.92 | — | — | |
| Trifluoroacetic Acid SCHEMBL20541013 | 0.92 | CA4 (0.38) | CA4CA2CA1CASP1FAHD1 | |
| Trifluoroacetic Acid SCHEMBL18797016 | 0.92 | CA4 (0.38) | CA4CA2CA1CASP1FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119390625-A | Preparation method of 1- (aryl sulfonyl) bicyclo [1.1.0] butane compound | 苏州百灵威超精细材料有限公司 | 2025-02-07 | — | — | CN | claimed |
| CN-119039115-A | Preparation method of 2, 6-difluoro-4-bromotrifluoromethoxybenzene | 大连奇凯医药科技有限公司 | 2024-11-29 | — | — | CN | claimed |
| CN-115505387-B | Toy safety detection material and preparation method thereof | 汕头市启龙玩具有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-118056805-A | Preparation method of trifluoroiodomethane | 浙江蓝天环保高科技股份有限公司 | 2024-05-21 | — | — | CN | claimed |
| CN-117946089-A | 3-Arylformyl coumarin intermediate compound and preparation method thereof | 苏州百灵威超精细材料有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117936901-A | Rechargeable magnesium battery amine electrolyte and preparation method and application thereof | 上海交通大学 | 2024-04-26 | — | — | CN | claimed |
| CN-113024539-B | Preparation method of isaconazole onium sulfate | 上海迪赛诺医药集团股份有限公司 | 2023-11-28 | — | — | CN | claimed |
| EP-3411362-B1 | A PROCESS FOR PREPARATION OF AN AROMATIC N-GLYCIDYLAMINE | GRASIM INDUSTRIES LTD (IN) | 2023-06-07 | — | — | EP | claimed |
| CN-111943813-B | Preparation method of cannabidiol compound | 上海特化医药科技有限公司 | 2023-04-14 | — | — | CN | claimed |
| CN-115724739-A | Resorcinol carboxylate metal complex, eutectic crystal or salt, and preparation method and application thereof | 山东特珐曼药业有限公司 | 2023-03-03 | — | — | CN | claimed |
| US-6124485-A | Process for producing 13-cis retinoic acid | ABBOTT LABORATORIES (US) | 2000-09-26 | — | — | US | claimed |
| EP-0078026-B1 | ANTIBIOTIC SYNTHESIS | MERCK & CO. INC. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0143075-B1 | PROCESS FOR THE PREPARATION OF N-GLYCIDYL COMPOUNDS | CIBA-GEIGY AG (CH) | 1987-11-19 | — | — | EP | claimed |
| EP-0125721-B1 | METHOD OF PROVIDING MAGNESIUM FLUORIDE LAYERS | Koninklijke Philips Electronics N.V. (NL) | 1987-04-01 | — | — | EP | claimed |
| US-4540769-A | NITRATE, PERCHLORATE, ALPHA-HALO CARBOXYLATE OR SULFONATE | CIBA-GEIGY CORPORATION (US) | 1985-09-10 | — | — | US | claimed |
| EP-0143075-A1 | Process for the preparation of N-glycidyl compounds | CIBA-GEIGY AG (CH) | 1985-05-29 | — | — | EP | claimed |
| US-4492721-A | Method of providing magnesium fluoride layers | U.S. PHILIPS CORPORATION (US) | 1985-01-08 | — | — | US | claimed |
| EP-0125721-A1 | Method of providing magnesium fluoride layers | Koninklijke Philips Electronics N.V. (NL) | 1984-11-21 | — | — | EP | claimed |
| US-4444685-A | Stereospecific synthesis of thienamycin from penicillin | MERCK & CO., INC. (US) | 1984-04-24 | — | — | US | claimed |
| EP-0078026-A2 | Antibiotic synthesis | MERCK & CO. INC. (US) | 1983-05-04 | — | — | EP | claimed |