SCHEMBL551145

SCHEMBL551145

CN1C2CCCC1CC(=O)C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 1.00
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
CHRNB4 P30926 2/20 0.38
CHRNA3 P32297 2/20 0.38
CHRM4 P08173 3/20 0.36
CHRM2 P08172 2/20 0.36
CHRM1 P11229 2/20 0.36
CHRM3 P20309 2/20 0.36
GSK3A P49840 1/20 0.35
GSK3B P49841 1/20 0.35
HTR3E A5X5Y0 1/20 0.33
HTR3B O95264 1/20 0.33
CHRM5 P08912 1/20 0.33
CHRNB2 P17787 1/20 0.33
HRH1 P35367 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
HTR3A P46098 1/20 0.33
TMEM97 Q5BJF2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13908059 1.00 MAPK1 (1.00) MAPK1MEN1KMT2ACHRNB4CHRNA3
Hydrochloric Acid SCHEMBL934612 0.98 MAPK1 (0.95) MAPK1MEN1KMT2ACHRNB4CHRNA3
SCHEMBL113383 0.90 MAPK1 (0.81) MAPK1MEN1KMT2ACHRNA7
SCHEMBL20906278 0.90 MAPK1 (0.81) MAPK1MEN1KMT2ACHRNA7
SCHEMBL6018054 0.90 MAPK1 (0.81) MAPK1MEN1KMT2ACHRNA7
SCHEMBL113382 0.90 MAPK1 (0.81) MAPK1MEN1KMT2ACHRNA7
Hydrochloric Acid SCHEMBL989897 0.87 MAPK1 (0.77) MAPK1MEN1KMT2ACHRNA7SIGMAR1
SCHEMBL18322806 0.82 MAPK1 (0.70) MAPK1MEN1KMT2A
SCHEMBL23475180 0.79 MAPK1 (0.65) MAPK1MEN1KMT2ACHRM4CHRM2
SCHEMBL3412272 0.79 MAPK1 (0.65) MAPK1MEN1KMT2ACHRM4CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 325 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243345-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE TOYO TIRE CORPORATION (JP) 2025-07-31 US claimed
US-20250243350-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE TOYO TIRE CORPORATION (JP) 2025-07-31 US claimed
US-11819535-B2 Composition and methods for regulating extracellular matrix accumulation UNIVERSITY HEALTH NETWORK (CA) 2023-11-21 US claimed
US-20080275241-A1 Polymorphic Forms of Dolasetron Base and Processes of Preparing Dolasetron Base, Its Polymorphic Forms and Salt Thereof USV LIMITED (IN) 2008-11-06 US claimed
WO-2007072507-A2 POLYMORPHIC FORMS OF DOLASETRON BASE AND PROCESSES OF PREPARING DOLASETRON BASE, ITS POLYMORPHIC FORMS AND SALT THEREOF USV LIMITED (IN) 2007-06-28 WO claimed
US-7144505-B2 Melt-spun polysulfone semipermeable membranes and methods for making the same BAXTER INTERNATIONAL INC. (US) 2006-12-05 US claimed
EP-1572331-A1 MELT-SPUN POLYSULFONE SEMIPERMEABLE MEMBRANES AND METHODS FOR MAKING THE SAME Baxter International Inc. (US) 2005-09-14 EP claimed
US-6881337-B2 Melt-spun polysulfone semipermeable membranes and methods for making the same BAXTER INTERNATIONAL INC. (US) 2005-04-19 US claimed
CN-1190436-C Process for preparing granisetron and its salt HAIZHENG PHARMACEUTICAL CO LTD (CN) 2005-02-23 CN claimed
WO-2004058385-A9 MELT-SPUN POLYSULFONE SEMIPERMEABLE MEMBRANES AND METHODS FOR MAKING THE SAME BAXTER INT (US) 2004-11-25 WO claimed
WO-2004058385-A1 MELT-SPUN POLYSULFONE SEMIPERMEABLE MEMBRANES AND METHODS FOR MAKING THE SAME BAXTER INTERNATIONAL INC. (US) 2004-07-15 WO claimed
US-20040026315-A1 Melt-spun polysulfone semipermeable membranes and methods for making the same BAXTER HEALTHCARE S.A. (CH) 2004-02-12 US claimed
CN-1451660-A Process for preparing granisetron and its salt HAIZHENG PHARMACEUTICAL CO LTD (CN) 2003-10-29 CN claimed
JP-2001507741-A 2001-06-12 JP claimed
US-20010003123-A1 Melt-spun polysulfone semipermeable membranes and methods for making the same MELUCH TIMOTHY B (US) 2001-06-07 US claimed
US-6218441-B1 USEFUL FOR LIQUID SEPARATION PROCESSES, SUCH AS, BUT NOT LIMITED TO, MICROFILTRATION, ULTRAFILTRATION, DIALYSIS, AND REVERSE OSMOSIS BAXTER INTERNATIONAL INC. 2001-04-17 US claimed
EP-0951498-A1 MELT-SPUN POLYSULFONE SEMIPERMEABLE MEMBRANES AND METHODS FOR MAKING THE SAME Althin Medical, Inc. (US) 1999-10-27 EP claimed
WO-1998029478-A1 MELT-SPUN POLYSULFONE SEMIPERMEABLE MEMBRANES AND METHODS FOR MAKING THE SAME ALTHIN MEDICAL, INC. (US) 1998-07-09 WO claimed
US-20250243350-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE TOYO TIRE CORPORATION (JP) 2025-07-31 US disclosed
WO-1984000166-A1 BENZOIC ACID PIPERIDYL ESTER DERIVATIVES AND METHOD OF PRODUCTION AND UTILIZATION THEREOF SANDOZ AG (CH) 1984-01-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080275241-A1 Polymorphic Forms of Dolasetron Base and Processes of Preparing Dolasetron Base, Its Polymorphic Forms and Salt Thereof CYP4A11, CYP3A43, VKORC1 MAPK1 2560/4885MEN1 2584/4885KMT2A 3853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.