SCHEMBL5511896

SCHEMBL5511896

COC(=O)N1CCC(N)(C(=O)Nc2ccc(N3CCOCC3=O)c(C)c2)C1

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5506783 0.91 F10 (0.51) F10
SCHEMBL5206095 0.88 F10 (0.54) F10
SCHEMBL5509687 0.87 F10 (0.51) F10
SCHEMBL5502780 0.87 F10 (0.53) F10
SCHEMBL3998054 0.87 F10 (0.52) F10
SCHEMBL5515679 0.87 F10 (0.58) F10
SCHEMBL5523153 0.85 F10 (0.52) F10
SCHEMBL5513705 0.85 F10 (0.54) F10
SCHEMBL5212485 0.85 F10 (0.54) F10
SCHEMBL5506478 0.84 F10 (0.53) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1747217-A1 NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS Boehringer Ingelheim International GmbH (DE) 2007-01-31 EP disclosed
WO-2005111029-A1 NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-11-24 WO disclosed