⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050731 | 0.69 | — | — | |
| SCHEMBL5512329 | 0.68 | — | — | |
| SCHEMBL1999107 | 0.64 | — | — | |
| SCHEMBL28856862 | 0.64 | — | — | |
| SCHEMBL4963218 | 0.64 | — | — | |
| SCHEMBL28319712 | 0.62 | — | — | |
| SCHEMBL27680736 | 0.61 | HRH3 (0.50) | — | |
| SCHEMBL28137559 | 0.61 | — | — | |
| SCHEMBL3194879 | 0.60 | — | — | |
| SCHEMBL28075275 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1016247-B | NOVEL COMPOUND OF IMIDAZOLE CARBOXILIC ACID DERIVATIVE | JANSSEN PHARMACEUTICA NV (BE) | 1992-04-15 | — | — | CN | claimed |
| CN-86104173-A | The preparation method of novel 5-imidazolyl carboxylic acid derivative and their use | — | 1987-01-28 | — | — | CN | claimed |
| EP-2719688-B1 | Process for producing tetrazolyloxime derivatives | NIPPON SODA CO (JP) | 2016-07-20 | — | — | EP | disclosed |
| EP-2719686-B1 | Process to halogenate a picoline derivative | NIPPON SODA CO (JP) | 2015-12-02 | — | — | EP | disclosed |
| EP-2719687-B1 | Process to make a bromopicoline derivative | NIPPON SODA CO (JP) | 2015-09-16 | — | — | EP | disclosed |
| US-9018385-B2 | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO., LTD. (JP) | 2015-04-28 | — | — | US | disclosed |
| US-9012653-B2 | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO., LTD. (JP) | 2015-04-21 | — | — | US | disclosed |
| US-9000178-B2 | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO., LTD. (JP) | 2015-04-07 | — | — | US | disclosed |
| US-8962848-B2 | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO., LTD. (JP) | 2015-02-24 | — | — | US | disclosed |
| US-8841458-B2 | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO., LTD. (JP) | 2014-09-23 | — | — | US | disclosed |
| US-20140155611-A1 | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 2014-06-05 | — | — | US | disclosed |
| EP-2546236-A1 | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | Nippon Soda Co., Ltd. (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-20130012713-A1 | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | NIPPON SODA CO., LTD | 2013-01-10 | — | — | US | disclosed |
| US-7223755-B2 | Hydroxymorpholinone derivative and medicinal use thereof | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2007-05-29 | — | — | US | disclosed |
| US-20050176704-A1 | Hydroxymorpholinone derivative and medicinal use thereof | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2005-08-11 | — | — | US | disclosed |
| CN-1090275-A | The prodrug of imidazole carboxylic acids as angiotensin II receptor antagonists | DU PONT (US) | 1994-08-03 | — | — | CN | disclosed |
| CN-1016247-B | NOVEL COMPOUND OF IMIDAZOLE CARBOXILIC ACID DERIVATIVE | JANSSEN PHARMACEUTICA NV (BE) | 1992-04-15 | — | — | CN | disclosed |
| CN-86104173-A | The preparation method of novel 5-imidazolyl carboxylic acid derivative and their use | — | 1987-01-28 | — | — | CN | disclosed |
| CN-86104173-A | The preparation method of novel 5-imidazolyl carboxylic acid derivative and their use | — | 1987-01-28 | — | — | CN | disclosed |
| CN-86104173-A | The preparation method of novel 5-imidazolyl carboxylic acid derivative and their use | — | 1987-01-28 | — | — | CN | disclosed |