SCHEMBL551259

SCHEMBL551259

Cc1ccc(I)c(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8840780 0.79
SCHEMBL3845672 0.75
SCHEMBL156450 0.75
SCHEMBL29352576 0.75
SCHEMBL30548753 0.75
SCHEMBL29587974 0.74
SCHEMBL333036 0.74
SCHEMBL3538617 0.72 AHR (0.55)
SCHEMBL1350393 0.72
SCHEMBL89325 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105063992-A Decoloring method of natural colored animal fibers NINGXIA RONGCHANG CASHMERE GROUP CO LTD 2015-11-18 CN claimed
US-6495540-B2 HEXAHYDROAZEPINE-2-ONE DERIVATIVE AS BETA-AMYLOID INHIBITOR BRISTOL - MYERS SQUIBB PHARMA COMPANY 2002-12-17 US claimed
US-20020010172-A1 Lactams as inhibitors of A-beta protein production BRISTOL-MYERS SQUIBB PHARMA COMPANY 2002-01-24 US claimed
CN-117683044-B Preparation method and application of asymmetric diaryl trithiophene/selenophene small molecular material UNIVERSITY OF CHINESE ACADEMY OF SCIENCES (CN) 2026-05-26 CN disclosed
WO-2026086794-A1 ANTIMICROBIAL COMPOUNDS AND METHODS OF USE THEREOF THE CHINESE UNIVERSITY OF HONG KONG (CN) 2026-04-30 WO disclosed
US-20250145596-A1 HETEROCYCLIC GLP-1 AGONISTS GASHERBRUM BIO, INC. 2025-05-08 US disclosed
EP-4476213-A1 HETEROCYCLIC GLP-1 AGONISTS Gasherbrum Bio, Inc. (US) 2024-12-18 EP disclosed
CN-119072474-A Heterocyclic GLP-1 agonists 加舒布鲁姆生物公司 2024-12-03 CN disclosed
CN-117683044-A Preparation method and application of asymmetric diaryl trithiophene/selenophene small molecular material 中国科学院大学 2024-03-12 CN disclosed
US-20230312481-A1 SUBSTITUTED (PHTHALAZIN-1-YLMETHYL)UREAS, SUBSTITUTED N-(PHTHALAZIN-1-YLMETHYL)AMIDES, AND ANALOGUES THEREOF ARBUTUS BIOPHARMA CORP (CA) 2023-10-05 US disclosed
US-20230295096-A1 PYRAZOLE CARBOXAMIDE COMPOUNDS FOR TREATMENT OF HBV ASSEMBLY BIOSCIENCES INC (US) 2023-09-21 US disclosed
US-5596006-A ANTIHYPERTENSIVE, ANTIATHEROSCLEROTIC AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1997-01-21 US disclosed
CN-1089260-A Trisubstituted biphenyls BAYER AG (DE) 1994-07-13 CN disclosed
EP-0594019-A1 Trisubstituted biphenyl as angiotensin II antagonistes BAYER AG (DE) 1994-04-27 EP disclosed
EP-0530338-A1 ANISOTROPIC ORGANIC COMPOUNDS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN (GB) 1993-03-10 EP disclosed
WO-1992016519-A2 ANISOTROPIC ORGANIC COMPOUNDS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1992-10-01 WO disclosed
EP-0078594-B1 TRIAZOLE DERIVATIVES, PROCESSES FOR PREPARING THEM, COMPOSITIONS CONTAINING THEM AND PROCESSES FOR COMBATING FUNGI AND REGULATING PLANT GROWTH IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-01-14 EP disclosed
US-4612381-A EPOXY INTERMEDIATES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-09-16 US disclosed
US-4496388-A FUNGICIDES; PLANT GROWTH REGULATORS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-01-29 US disclosed
EP-0078594-A1 Triazole derivatives, processes for preparing them, compositions containing them and processes for combating fungi and regulating plant growth IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-05-11 EP disclosed