Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.76 |
| ▸ | PPARA | Q07869 | 15/20 | 0.76 |
| ▸ | PPARG | P37231 | 8/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5511919 | 0.91 | PPARD (0.63) | PPARDPPARAPPARG | |
| SCHEMBL5513213 | 0.86 | PPARD (1.00) | PPARDPPARAPPARG | |
| SCHEMBL5513436 | 0.84 | PPARD (0.76) | PPARDPPARAPPARG | |
| SCHEMBL5514485 | 0.84 | PPARD (0.82) | PPARDPPARAPPARG | |
| SCHEMBL5509858 | 0.84 | PPARD (0.82) | PPARDPPARAPPARG | |
| SCHEMBL5510532 | 0.84 | PPARD (0.82) | PPARDPPARAPPARG | |
| SCHEMBL5506830 | 0.83 | PPARD (1.00) | PPARDPPARAPPARG | |
| SCHEMBL6201341 | 0.82 | PPARD (0.59) | PPARDPPARAPPARG | |
| Lithium SCHEMBL6314015 | 0.82 | PPARD (0.58) | PPARDPPARAPPARG | |
| SCHEMBL6314006 | 0.82 | PPARD (0.58) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39916-E1 | Compounds that modulate PPAR activity and methods for their preparation | WARNER LAMBERT COMPANY (US) | 2007-11-06 | — | — | US | disclosed |
| US-RE39916-E1 | Compounds that modulate PPAR activity and methods for their preparation | WARNER LAMBERT COMPANY (US) | 2007-11-06 | — | — | US | disclosed |