Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.41 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | UGCG | Q16739 | 2/20 | 0.33 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12481795 | 0.88 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL15033887 | 0.88 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL4313163 | 0.88 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL49884 | 0.88 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL1127982 | 0.88 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL15268272 | 0.88 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL13810709 | 0.88 | — | — | |
| SCHEMBL15383241 | 0.88 | — | — | |
| SCHEMBL2510810 | 0.87 | TSHR (0.50) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| Cyclohexane SCHEMBL960269 | 0.85 | TSHR (0.62) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384921-B | Polyimide precursor composition and method for producing polyimide film using same | 东进世美肯株式会社 | 2023-07-18 | — | — | CN | claimed |
| CN-109384922-B | Polyimide precursor composition and method for producing polyimide film using same | 东进世美肯株式会社 | 2023-07-14 | — | — | CN | claimed |
| CN-1136250-C | Crosslinked solid polyelectrolytes and their use | ������������ʽ���� | 2004-01-28 | — | — | CN | claimed |
| CN-1215416-A | Crss-linked solid polyelectrolyte and use thereof | DAISO CO LTD (JP) | 1999-04-28 | — | — | CN | claimed |
| EP-3638705-B1 | INTRAOCULAR LENS COMPOSITIONS | ALCON INC (CH) | 2024-02-28 | — | — | EP | disclosed |
| CN-110027766-B | Applicator for die cut pieces and method and die cut piece strip for applying die cut pieces to a surface | 德莎欧洲股份公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-113166594-B | Potentially reactive adhesive film | 德莎欧洲股份公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-109384921-B | Polyimide precursor composition and method for producing polyimide film using same | 东进世美肯株式会社 | 2023-07-18 | — | — | CN | disclosed |
| CN-109384922-B | Polyimide precursor composition and method for producing polyimide film using same | 东进世美肯株式会社 | 2023-07-14 | — | — | CN | disclosed |
| US-11642217-B2 | Intraocular lens compositions | ALCON INC. (CH) | 2023-05-09 | — | — | US | disclosed |
| CN-111491795-B | Packaging film | 株式会社LG化学 | 2023-01-10 | — | — | CN | disclosed |
| CN-110657145-B | Applicator for die-cut pieces and method for applying die-cut pieces to a surface and a strip of die-cut pieces | 德莎欧洲股份公司 | 2022-04-05 | — | — | CN | disclosed |
| US-20020099220-A1 | Calcilytic compounds | NPS PHARMACEUTICALS, INC. | 2002-07-25 | — | — | US | disclosed |
| EP-0764506-B1 | PROCESS FOR PRODUCING MULTI-LAYER MOLDED ARTICLES | ARACO KK (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-6022894-A | Method of using calcilytic compounds | NPS PHARMACEUTICALS, INC. (US) | 2000-02-08 | — | — | US | disclosed |
| US-5961902-A | Manufacturing method for molded multilayer article | ARACO KABUSHIKI KAISHA (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0901459-A1 | CALCILYTIC COMPOUNDS | NPS PHARMACEUTICALS, INC. (US) | 1999-03-17 | — | — | EP | disclosed |
| US-5712342-A | Process for producing a water-dispersion of polyurethane resin and a paint composition containing the resin produced by that process | KOREA CHEMICAL CO., LTD. (KR) | 1998-01-27 | — | — | US | disclosed |
| WO-1997037967-A1 | CALCILYTIC COMPOUNDS | NPS PHARMACEUTICALS, INC. (US) | 1997-10-16 | — | — | WO | disclosed |
| EP-0764506-A1 | PROCESS FOR PRODUCING MULTI-LAYER MOLDED ARTICLES | ARACO KABUSHIKI KAISHA (JP) | 1997-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099220-A1 | Calcilytic compounds | CALCR, CASR, CALCRL | TSHR 953/4885SMN1; SMN2 4117/4885ALDH1A1 4285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.