Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23421089 | 0.85 | TLR8 (0.34) | TLR7TLR8DHFR | |
| SCHEMBL18588106 | 0.84 | TLR8 (0.42) | TLR7TLR8DHFR | |
| SCHEMBL23421520 | 0.79 | TLR8 (0.33) | TLR7TLR8 | |
| SCHEMBL17204268 | 0.77 | TLR7 (0.45) | TLR7TLR8 | |
| SCHEMBL4654594 | 0.77 | TLR7 (0.39) | TLR7TLR8 | |
| SCHEMBL5271662 | 0.75 | TLR8 (0.43) | TLR8DHFR | |
| SCHEMBL23421036 | 0.75 | TLR8 (0.33) | TLR7TLR8DHFR | |
| SCHEMBL20624057 | 0.74 | TLR8 (0.40) | TLR7TLR8 | |
| SCHEMBL4763415 | 0.74 | TLR7 (0.49) | TLR7TLR8 | |
| SCHEMBL23421518 | 0.73 | TLR8 (0.37) | TLR7TLR8DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1850849-A2 | METHOD OF PREFERENTIALLY INDUCING THE BIOSYNTHESIS OF INTERFERON | Coley Pharmaceutical Group, Inc. (US) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006091647-A2 | METHOD OF PREFERENTIALLY INDUCING THE BIOSYNTHESIS OF INTERFERON | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-08-31 | — | — | WO | disclosed |