Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29104414 | 0.84 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1TDP1SLC7A5 | |
| SCHEMBL12868854 | 0.84 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1TDP1SLC7A5 | |
| SCHEMBL12868857 | 0.84 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1TDP1SLC7A5 | |
| SCHEMBL5509916 | 0.81 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1TDP1SLC7A5 | |
| SCHEMBL5512967 | 0.81 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1TDP1SLC7A5 | |
| SCHEMBL20239746 | 0.77 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1TDP1SLC7A5 | |
| SCHEMBL15905686 | 0.76 | GABRR1 (0.41) | TP53 | |
| SCHEMBL19918461 | 0.76 | GABRR1 (0.41) | TP53 | |
| SCHEMBL10266069 | 0.76 | GABRR1 (0.41) | TP53 | |
| SCHEMBL24038806 | 0.74 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1TDP1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |