SCHEMBL5514680

SCHEMBL5514680

CNC(=O)c1cc2c(n(CCOC)c1=O)CCCCCC2

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 0.73
CNR1 P21554 14/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11922831 0.90 CNR2 (0.70) CNR2CNR1
SCHEMBL5508222 0.89 CNR2 (0.77) CNR2CNR1
SCHEMBL5508845 0.88 CNR2 (0.69) CNR2CNR1
SCHEMBL5509460 0.85 CNR2 (0.79) CNR2CNR1
SCHEMBL5515472 0.84 CNR2 (0.74) CNR2CNR1
SCHEMBL14865355 0.84 CNR2 (0.66) CNR2CNR1
SCHEMBL2746066 0.82 CNR2 (0.64) CNR2CNR1
SCHEMBL2736562 0.82 CNR2 (0.52) CNR2CNR1
SCHEMBL5511938 0.81 CNR2 (0.60) CNR2CNR1
SCHEMBL2746608 0.80 CNR2 (0.70) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8367666-B2 3-carbamoyl-2-pyridone derivatives SHIONOGI & CO., LTD. (JP) 2013-02-05 US disclosed
US-8178681-B2 methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency SHIONOGI & CO., LTD. (JP) 2012-05-15 US disclosed
EP-1806342-A1 3-CARBAMOYL-2-PYRIDONE DERIVATIVE SHIONOGI & CO., LTD. (JP) 2007-07-11 EP disclosed