SCHEMBL5514840

SCHEMBL5514840

CCCCCCCCCOC(=O)C1CC=CCC1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.54
MAPK1 P28482 1/20 0.48
PPARG P37231 3/20 0.48
CHRM2 P08172 2/20 0.44
CHRM4 P08173 2/20 0.44
CHRM5 P08912 2/20 0.44
CHRM1 P11229 2/20 0.44
CHRM3 P20309 2/20 0.44
NAAA Q02083 1/20 0.43
HCAR2 Q8TDS4 1/20 0.41
EPHX1 P07099 1/20 0.41
TSHR P16473 2/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5515120 1.00 POLB (0.54) POLBMAPK1PPARGCHRM2CHRM4
SCHEMBL5516861 1.00 POLB (0.54) POLBMAPK1PPARGCHRM2CHRM4
SCHEMBL5515166 1.00 POLB (0.54) POLBMAPK1PPARGCHRM2CHRM4
SCHEMBL5515383 1.00 POLB (0.54) POLBMAPK1PPARGCHRM2CHRM4
SCHEMBL5514888 1.00 POLB (0.54) POLBMAPK1PPARGCHRM2CHRM4
SCHEMBL5518200 1.00 POLB (0.54) POLBMAPK1PPARGCHRM2CHRM4
SCHEMBL5524004 1.00 POLB (0.54) POLBMAPK1PPARGCHRM2CHRM4
SCHEMBL5512498 1.00 POLB (0.54) POLBMAPK1PPARGCHRM2CHRM4
SCHEMBL5516869 1.00 POLB (0.54) POLBMAPK1PPARGCHRM2CHRM4
SCHEMBL5517016 1.00 POLB (0.54) POLBMAPK1PPARGCHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3238690-B1 BAG FOR MEDICAL USE KAWASUMI LAB INC (JP) 2022-09-14 EP claimed
EP-3238690-A1 BAG FOR MEDICAL USE Kawasumi Laboratories, Inc. (JP) 2017-11-01 EP claimed
EP-3238690-B1 BAG FOR MEDICAL USE KAWASUMI LAB INC (JP) 2022-09-14 EP disclosed
EP-3238690-A1 BAG FOR MEDICAL USE Kawasumi Laboratories, Inc. (JP) 2017-11-01 EP disclosed
EP-3238690-A1 BAG FOR MEDICAL USE Kawasumi Laboratories, Inc. (JP) 2017-11-01 EP disclosed
WO-2016121692-A1 BAG FOR MEDICAL USE 川澄化学工業株式会社 2016-08-04 WO disclosed
US-7282601-B2 Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester NEW JAPAN CHEMICAL CO., LTD. (JP) 2007-10-16 US disclosed
US-20050038283-A1 Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester NEW JAPAN CHEMICAL, CO., LTD. (JP) 2005-02-17 US disclosed
EP-1227078-A1 DICARBOXYLIC DIESTER, PROCESS FOR PRODUCING THE SAME, AND REFRIGERATING MACHINE LUBRICATING OIL COMPRISING THE ESTER NEW JAPAN CHEMICAL CO.,LTD. (JP) 2002-07-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038283-A1 Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester SCO2, PDHX, DECR2 POLB 893/4885MAPK1 2408/4885PPARG 99/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.