Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509408 | 0.95 | EGFR (0.81) | EGFRKDR | |
| SCHEMBL5509392 | 0.93 | EGFR (0.70) | EGFRKDR | |
| SCHEMBL5510867 | 0.90 | EGFR (0.75) | EGFRKDR | |
| SCHEMBL4577855 | 0.90 | EGFR (0.89) | EGFRKDR | |
| SCHEMBL5511525 | 0.90 | KDR (0.67) | EGFRKDR | |
| SCHEMBL16105100 | 0.85 | EGFR (0.92) | EGFRKDR | |
| SCHEMBL5510826 | 0.84 | EGFR (0.59) | EGFRKDR | |
| SCHEMBL5091125 | 0.84 | EGFR (1.00) | EGFRKDR | |
| SCHEMBL5512911 | 0.84 | EGFR (0.69) | EGFRKDR | |
| SCHEMBL4577754 | 0.83 | EGFR (1.00) | EGFRKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007055513-A1 | QUINAZOLINE DERIVATIVES AS A SIGNAL TRANSDUCTION INHIBITOR AND METHOD FOR THE PREPARATION THEREOF | HANMI PHARM. CO., LTD. (KR) | 2007-05-18 | — | — | WO | disclosed |