SCHEMBL5515192

SCHEMBL5515192

COC(=O)CNC(=O)c1cc2c(n(CCN3CCCCC3)c1=O)CCCCCC2

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 0.57
CNR1 P21554 14/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5524431 0.88 CNR2 (0.68) CNR2CNR1
SCHEMBL2746550 0.83 CNR2 (0.72) CNR2CNR1
SCHEMBL5514433 0.83 CNR2 (0.80) CNR2CNR1
SCHEMBL5524553 0.81 CNR2 (0.71) CNR2CNR1
SCHEMBL5516847 0.81 CNR2 (0.51) CNR2CNR1
SCHEMBL5521266 0.80 CNR2 (0.62) CNR2CNR1
SCHEMBL5520969 0.80 CNR2 (0.62) CNR2CNR1
SCHEMBL2746879 0.80 CNR2 (0.62) CNR2CNR1
SCHEMBL2746100 0.79 CNR2 (0.71) CNR2CNR1
SCHEMBL2737017 0.79 CNR2 (0.72) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8367666-B2 3-carbamoyl-2-pyridone derivatives SHIONOGI & CO., LTD. (JP) 2013-02-05 US disclosed
US-8367666-B2 3-carbamoyl-2-pyridone derivatives SHIONOGI & CO., LTD. (JP) 2013-02-05 US disclosed
US-8178681-B2 methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency SHIONOGI & CO., LTD. (JP) 2012-05-15 US disclosed
US-8178681-B2 methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency SHIONOGI & CO., LTD. (JP) 2012-05-15 US disclosed