Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 16/20 | 0.54 |
| ▸ | PRKCD | Q05655 | 16/20 | 0.54 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | LYN | P07948 | 1/20 | 0.45 |
| ▸ | HCK | P08631 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | PRKCH | P24723 | 1/20 | 0.45 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5520629 | 0.92 | PRKCQ (0.53) | PRKCQPRKCDLCKFYNLYN | |
| SCHEMBL5513949 | 0.90 | PRKCQ (0.53) | PRKCQPRKCDLCKFYNLYN | |
| SCHEMBL27718535 | 0.81 | PRKCQ (0.48) | PRKCQPRKCDLCKFYNLYN | |
| SCHEMBL5524338 | 0.78 | PRKCQ (0.71) | PRKCQPRKCDLCKFYNLYN | |
| SCHEMBL5522385 | 0.78 | PRKCQ (0.46) | PRKCQPRKCDLCKLYNPRKCH | |
| SCHEMBL5531730 | 0.76 | PRKCQ (0.77) | PRKCQPRKCDLCKFYNLYN | |
| SCHEMBL4947985 | 0.75 | PRKCQ (0.76) | PRKCQPRKCDLCKFYNLYN | |
| SCHEMBL5530118 | 0.75 | ABL1 (0.47) | PRKCQPRKCD | |
| SCHEMBL5520863 | 0.73 | PRKCQ (0.46) | PRKCQPRKCDLCKLYNPRKCH | |
| SCHEMBL5527268 | 0.72 | PRKCQ (0.43) | PRKCQPRKCDLCKFYNLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070082880-A1 | Thieno [2,3-B] pyridine-5-carbonitriles as protein kinase inhibitors | WYETH | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082880-A1 | Thieno [2,3-B] pyridine-5-carbonitriles as protein kinase inhibitors | MAP4K2, CNKSR1, MAP3K1 | PRKCQ 286/4885PRKCD 356/4885RIPK1 292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.