SCHEMBL5515951

SCHEMBL5515951

C=C[C@@H](C)N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL130823 1.00
SCHEMBL15015245 1.00
Hydrochloric Acid SCHEMBL3264665 0.96
Iodide SCHEMBL28838224 0.96
Hydrochloric Acid SCHEMBL4624433 0.96
Hydrochloric Acid SCHEMBL4623997 0.96
Hydrochloric Acid SCHEMBL15561491 0.96
Urea SCHEMBL4529306 0.83
Ethylene Glycol SCHEMBL2364123 0.83
SCHEMBL6565675 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250188089-A1 SUBSTITUTED PYRIDOTRIAZINE COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2025-06-12 US disclosed
US-20250115619-A1 BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE GILEAD SCIENCES, INC. 2025-04-10 US disclosed
CN-119462659-A Bridged tricyclic carbamoyl pyridone compounds and pharmaceutical uses thereof 吉利德科学公司 2025-02-18 CN disclosed
US-12227520-B2 Bridged tricyclic carbamoylpyridone compounds and their pharmaceutical use GILEAD SCIENCES, INC. (US) 2025-02-18 US disclosed
US-12187734-B2 Substituted pyridotriazine compounds and uses thereof GILEAD SCIENCES, INC. (US) 2025-01-07 US disclosed
CN-113874079-B Bridged tricyclic carbamoyl pyridone compounds and pharmaceutical uses thereof 吉利德科学公司 2024-11-08 CN disclosed
EP-4196479-B9 SUBSTITUTED PYRIDOTRIAZINE COMPOUNDS AND USES THEREOF GILEAD SCIENCES INC (US) 2024-10-16 EP disclosed
US-20240300966-A1 SUBSTITUTED PYRIDOTRIAZINE COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2024-09-12 US disclosed
CN-115885026-B Viscosity index improver composition and lubricating oil composition 三洋化成工业株式会社 2024-06-21 CN disclosed
EP-4321217-A2 SUBSTITUTED PYRIDOTRIAZINE COMPOUNDS AND USES THEREOF Gilead Sciences, Inc. (US) 2024-02-14 EP disclosed
EP-2740728-A1 URACIL DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES Dainippon Sumitomo Pharma Co., Ltd. (JP) 2014-06-11 EP disclosed
WO-2014022752-A1 MACROCYCLES AS PIM INHIBITORS AMGEN INC. (US) 2014-02-06 WO disclosed
WO-2014022752-A1 MACROCYCLES AS PIM INHIBITORS AMGEN INC. (US) 2014-02-06 WO disclosed
US-8299507-B2 Semiconductor device KABUSHIKI KAISHA TOSHIBA (JP) 2012-10-30 US disclosed
US-20110105389-A1 Macrocyclic Ghrelin Receptor Antagonists and Inverse Agonists and Methods of Using the Same OCERA THERAPEUTICS, INC. 2011-05-05 US disclosed
US-20100224916-A1 SEMICONDUCTOR DEVICE KABUSHIKI KAISHA TOSHIBA (JP) 2010-09-09 US disclosed
US-7173059-B2 Intermediates useful in the synthesis of HIV-protease inhibitors and methods for preparing the same AGOURON PHARMACEUTICALS, INC. (US) 2007-02-06 US disclosed
EP-1633704-A2 INTERMEDIATES USEFUL IN THE SYNTHESIS OF HIV-PROTEASE INHIBITORS AND METHODS FOR PREPARING THE SAME PFIZER INC. (US) 2006-03-15 EP disclosed
US-20050250949-A1 Intermediates useful in the synthesis of HIV-protease inhibitors and methods for preparing the same AGOURON PHARMACEUTICALS INC. 2005-11-10 US disclosed
WO-2004099129-A2 INTERMEDIATES USEFUL IN THE SYNTHESIS OF HIV-PROTEASE INHIBITORS AND METHODS FOR PREPARING THE SAME PFIZER INC. (US) 2004-11-18 WO disclosed