Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.45 |
| ▸ | CCR1 | P32246 | 4/20 | 0.41 |
| ▸ | OGA | O60502 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 4/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5528350 | 1.00 | HIF1A (0.45) | HIF1ACCR1OGACTSBCTSS | |
| SCHEMBL14453016 | 1.00 | HIF1A (0.45) | HIF1ACCR1OGACTSBCTSS | |
| SCHEMBL5516800 | 1.00 | HIF1A (0.45) | HIF1ACCR1OGACTSBCTSS | |
| SCHEMBL4710665 | 0.83 | POLB (0.45) | HIF1ACCR1PTGDRDPP4 | |
| SCHEMBL4709141 | 0.83 | POLB (0.45) | HIF1ACCR1PTGDRDPP4 | |
| SCHEMBL4710679 | 0.83 | POLB (0.45) | HIF1ACCR1PTGDRDPP4 | |
| SCHEMBL4709090 | 0.82 | OGA (0.53) | HIF1ACCR1OGASUV39H2 | |
| SCHEMBL4709091 | 0.82 | OGA (0.53) | HIF1ACCR1OGASUV39H2 | |
| SCHEMBL4710264 | 0.82 | OGA (0.53) | HIF1ACCR1OGASUV39H2 | |
| SCHEMBL14453004 | 0.81 | OGA (0.38) | HIF1AOGACTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241765-B2 | Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues | NEUROGEN CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |