Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.74 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.74 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646326 | 1.00 | DPP4 (0.74) | DPP4DPP9DPP8AVPR1A | |
| SCHEMBL645584 | 0.88 | DPP4 (0.68) | DPP4DPP9DPP8 | |
| SCHEMBL648011 | 0.85 | DPP4 (1.00) | DPP4DPP9DPP8 | |
| SCHEMBL646174 | 0.85 | DPP4 (0.80) | DPP4DPP9DPP8 | |
| SCHEMBL647408 | 0.85 | DPP4 (0.64) | DPP4DPP9DPP8 | |
| SCHEMBL645951 | 0.85 | DPP4 (0.80) | DPP4DPP9DPP8 | |
| SCHEMBL5525634 | 0.85 | DPP4 (0.64) | DPP4DPP9DPP8 | |
| SCHEMBL5633737 | 0.85 | DPP4 (0.80) | DPP4DPP9DPP8 | |
| SCHEMBL6250940 | 0.85 | DPP4 (0.80) | DPP4DPP9DPP8 | |
| SCHEMBL647592 | 0.84 | DPP4 (0.65) | DPP4DPP9DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238724-B2 | Antidiabetic agents; hyperlipemic agents; obestity; immunomoderator; atherosclerosis | ABBOTT LABORATORIES (US) | 2007-07-03 | — | — | US | claimed |
| EP-1560811-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004026822-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2004-04-01 | — | — | WO | disclosed |