Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.83 |
| ▸ | CA2 | P00918 | 1/20 | 0.83 |
| ▸ | CA9 | Q16790 | 1/20 | 0.83 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL27573184 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL19576 | 1.00 | — | — | |
| Bicarbonate SCHEMBL19574 | 1.00 | — | — | |
| Bicarbonate SCHEMBL28222232 | 0.93 | — | — | |
| Bicarbonate SCHEMBL5586500 | 0.93 | — | — | |
| Bicarbonate SCHEMBL28312870 | 0.93 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL28208651 | 0.93 | — | — | |
| Bicarbonate SCHEMBL28861953 | 0.93 | — | — | |
| Bicarbonate SCHEMBL28689455 | 0.93 | — | — | |
| Bicarbonate SCHEMBL28972943 | 0.93 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117344382-A | Compound alkali metal borophosphate and alkali metal borophosphate nonlinear optical crystal, and preparation method and application thereof | 天津理工大学 | 2024-01-05 | — | — | CN | claimed |
| US-20230416093-A1 | Compounds Alkali Metal Borophosphates, Alkali Metal Borophosphates Nonlinear Optical Crystals as well as Preparation Method and Application thereof | TIANJIN UNIVERSITY OF TECHNOLOGY (CN) | 2023-12-28 | — | — | US | claimed |
| CN-113668056-B | Compound molybdenum zinc potassium phosphate and molybdenum zinc potassium phosphate nonlinear optical crystal, preparation method and application | 天津理工大学 | 2023-11-24 | — | — | CN | claimed |
| CN-115353623-B | Polyimide photosensitive material and preparation method and application thereof | 中山大学 | 2023-10-13 | — | — | CN | claimed |
| CN-115353623-A | Polyimide photosensitive material and preparation method and application thereof | 中山大学 | 2022-11-18 | — | — | CN | claimed |
| CN-113846379-A | Compound bismuth cadmium phosphate and bismuth cadmium phosphate scintillation crystal, and preparation method and application thereof | 天津理工大学 | 2021-12-28 | — | — | CN | claimed |
| CN-113668055-A | Compound potassium molybdenum phosphate and potassium molybdenum phosphate nonlinear optical crystal, and preparation method and application thereof | 天津理工大学 | 2021-11-19 | — | — | CN | claimed |
| CN-113668056-A | Compound molybdenum zinc potassium phosphate and molybdenum zinc potassium phosphate nonlinear optical crystal, and preparation method and application thereof | 天津理工大学 | 2021-11-19 | — | — | CN | claimed |
| US-7601881-B2 | Isomerization catalyst and process | UOP LLC (US) | 2009-10-13 | — | — | US | claimed |
| US-7538064-B2 | Isomerization catalyst and process | UOP LLC (US) | 2009-05-26 | — | — | US | claimed |
| US-20080100124-A1 | Tool with a Large Volume of a Superhard Material | SCHLUMBERGER TECHNOLOGY CORPORATION | 2008-05-01 | — | — | US | claimed |
| US-20080099249-A1 | TOOL WITH A LARGE VOLUME OF A SUPERHARD MATERIAL | SCHLUMBERGER TECHNOLOGY CORPORATION | 2008-05-01 | — | — | US | claimed |
| US-7353893-B1 | Tool with a large volume of a superhard material | SCHLUMBERGER TECHNOLOGY CORPORATION | 2008-04-08 | — | — | US | claimed |
| CN-1317246-C | Process for reducing alpha-haloketones to secondary alpha-halohydrins | DOW GLOBAL TECHNOLOGY CO (US) | 2007-05-23 | — | — | CN | claimed |
| US-20060094919-A1 | Isomerization catalyst and process | UOP LLC | 2006-05-04 | — | — | US | claimed |
| US-20060094592-A1 | Isomerization catalyst and process | UOP LLC | 2006-05-04 | — | — | US | claimed |
| CN-1625539-A | Process for the reduction of a-haloketones to secondary a-halohydrins | DOW GLOMAUGHON BOB R (US) | 2005-06-08 | — | — | CN | claimed |
| EP-0701861-B1 | A diamond sintered body and a process for the production of the same, tools and abrasive grains using the same | SUMITOMO ELECTRIC INDUSTRIES (JP) | 2004-11-17 | — | — | EP | claimed |
| US-5912217-A | DIAMONDS AND BREAKAGE RESISTANCE, CORROSION RESISTANCE, HEAT RESISTANCE AND WEAR RESISTANCE | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1999-06-15 | — | — | US | claimed |
| EP-0701861-A2 | A diamond sintered body and a process for the production of the same, tools and abrasive grains using the same | Sumitomo Electric Industries, Ltd. (JP) | 1996-03-20 | — | — | EP | claimed |