Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | ARG1 | P05089 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5762804 | 0.98 | CYP1A2 (0.44) | CYP1A2ALOX15CYP2C19MEN1ALDH1A1 | |
| SCHEMBL10151351 | 0.83 | PIM2 (0.38) | CYP1A2ALOX15CYP2C19ALDH1A1KMT2A | |
| SCHEMBL21035123 | 0.83 | PIM2 (0.38) | CYP1A2ALOX15CYP2C19ALDH1A1KMT2A | |
| SCHEMBL15206338 | 0.83 | PIM2 (0.38) | CYP1A2ALOX15CYP2C19ALDH1A1KMT2A | |
| SCHEMBL15206340 | 0.83 | PIM2 (0.38) | CYP1A2ALOX15CYP2C19ALDH1A1KMT2A | |
| SCHEMBL30066149 | 0.80 | GRIN2D (0.41) | CYP1A2ALOX15CYP2C19MEN1ALDH1A1 | |
| SCHEMBL689400 | 0.80 | CYP2D6 (0.52) | CYP1A2ALOX15CYP2C19MEN1THRB | |
| SCHEMBL7361978 | 0.80 | CYP2D6 (0.52) | CYP1A2ALOX15CYP2C19MEN1THRB | |
| SCHEMBL7338708 | 0.80 | CYP2D6 (0.52) | CYP1A2ALOX15CYP2C19MEN1THRB | |
| SCHEMBL7338717 | 0.80 | CYP2D6 (0.52) | CYP1A2ALOX15CYP2C19MEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199105-B2 | Lincomycin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS, INC. (US) | 2007-04-03 | — | — | US | claimed |
| US-7199105-B2 | Lincomycin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS, INC. (US) | 2007-04-03 | — | — | US | disclosed |
| US-7164011-B2 | Lincomycin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS, INC. (US) | 2007-01-16 | — | — | US | disclosed |
| EP-1654268-A2 | LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005007665-A2 | LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2005-01-27 | — | — | WO | disclosed |