Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5519607 | 1.00 | CXCR4 (0.58) | CXCR4NPC1RAB9AHDAC1HDAC6 | |
| SCHEMBL16083006 | 0.89 | CXCR4 (0.69) | CXCR4NPC1RAB9AHDAC1HDAC6 | |
| SCHEMBL2934330 | 0.89 | CXCR4 (0.69) | CXCR4NPC1RAB9AHDAC1HDAC6 | |
| SCHEMBL11217673 | 0.85 | CXCR4 (0.56) | CXCR4NPC1RAB9AHDAC1HDAC6 | |
| SCHEMBL11217670 | 0.85 | CXCR4 (0.56) | CXCR4NPC1RAB9AHDAC1HDAC6 | |
| SCHEMBL5519379 | 0.82 | CXCR4 (0.61) | CXCR4NPC1RAB9AHDAC1HDAC6 | |
| SCHEMBL4288126 | 0.82 | CXCR4 (0.61) | CXCR4NPC1RAB9AHDAC1HDAC6 | |
| SCHEMBL7330860 | 0.82 | CXCR4 (0.61) | CXCR4NPC1RAB9AHDAC1HDAC6 | |
| SCHEMBL20577479 | 0.82 | CXCR4 (0.54) | CXCR4NPC1RAB9AHDAC1HDAC6 | |
| SCHEMBL23023087 | 0.82 | CXCR4 (0.65) | CXCR4NPC1RAB9AHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167452-A1 | Therapeutic amide derivatives | PFIZER, INC. | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167452-A1 | Therapeutic amide derivatives | GRIN1, GRIN2B, GRIN3A | CXCR4 1958/4885NPC1 1340/4885RAB9A 3372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.