Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.44 |
| ▸ | CNR1 | P21554 | 5/20 | 0.44 |
| ▸ | TACR3 | P29371 | 10/20 | 0.42 |
| ▸ | TACR2 | P21452 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5515333 | 0.93 | CNR2 (0.47) | CNR2CNR1TACR3TACR2TSHR | |
| SCHEMBL5522309 | 0.91 | CNR2 (0.48) | CNR2CNR1MEN1KMT2A | |
| SCHEMBL27680158 | 0.85 | CNR2 (0.63) | CNR2CNR1TACR3TACR2TSHR | |
| SCHEMBL5516235 | 0.84 | CNR2 (0.52) | CNR2CNR1KMT2A | |
| SCHEMBL2746600 | 0.82 | CNR2 (0.48) | CNR2CNR1TACR3KDM4EMEN1 | |
| SCHEMBL5517650 | 0.82 | CNR2 (0.48) | CNR2CNR1TACR3KDM4EMEN1 | |
| SCHEMBL5519688 | 0.82 | CNR2 (0.61) | CNR2CNR1TACR3TACR2TSHR | |
| SCHEMBL27660174 | 0.82 | CNR2 (0.61) | CNR2CNR1TACR3TACR2TSHR | |
| SCHEMBL5519973 | 0.79 | CNR2 (0.50) | CNR2CNR1TACR3KDM4EALDH1A1 | |
| SCHEMBL2745553 | 0.79 | CNR2 (0.50) | CNR2CNR1TACR3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |