Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | FCER2 | P06734 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10268771 | 0.82 | ACE (0.58) | ACECYP2C19PPARGPPARAMETAP2 | |
| SCHEMBL1357871 | 0.82 | ACE (0.58) | ACECYP2C19PPARGPPARAMETAP2 | |
| SCHEMBL1741031 | 0.82 | ACE (0.58) | ACECYP2C19PPARGPPARAMETAP2 | |
| SCHEMBL5418068 | 0.78 | CYP1A2 (0.55) | ACECYP2C19PPARGPPARA | |
| SCHEMBL28519174 | 0.78 | CYP2C19 (0.46) | ACECYP2C19PPARGPPARAMMP1 | |
| SCHEMBL9226840 | 0.77 | ACE (0.50) | ACECYP2C19PPARGPPARAMMP1 | |
| SCHEMBL2162954 | 0.77 | CYP2C19 (0.52) | ACECYP2C19PPARGPPARAMETAP2 | |
| SCHEMBL5846128 | 0.77 | CYP2C19 (0.52) | ACECYP2C19PPARGPPARAMETAP2 | |
| SCHEMBL723034 | 0.77 | CYP2C19 (0.52) | ACECYP2C19PPARGPPARAMETAP2 | |
| SCHEMBL8500821 | 0.76 | CYP1A2 (0.53) | ACECYP2C19PPARGPPARAMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |