Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 6/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 13/20 | 0.80 |
| ▸ | HSP90AB1 | P08238 | 13/20 | 0.80 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30583202 | 0.89 | HSP90AA1 (1.00) | ERBB2HSP90AA1HSP90AB1HSP90B1ADORA2A | |
| SCHEMBL1964201 | 0.89 | HSP90AA1 (1.00) | ERBB2HSP90AA1HSP90AB1HSP90B1ADORA2A | |
| SCHEMBL1965706 | 0.88 | ERBB2 (1.00) | ERBB2HSP90AA1HSP90AB1ADORA2AADORA2B | |
| SCHEMBL1963379 | 0.88 | ERBB2 (1.00) | ERBB2HSP90AA1HSP90AB1HSP90B1ADORA2A | |
| SCHEMBL1964339 | 0.85 | HSP90AA1 (0.76) | ERBB2HSP90AA1HSP90AB1HSP90B1ADORA2A | |
| SCHEMBL4320278 | 0.84 | HSP90AA1 (0.77) | ERBB2HSP90AA1HSP90AB1HSP90B1ADORA2A | |
| SCHEMBL30583297 | 0.84 | HSP90AA1 (0.77) | ERBB2HSP90AA1HSP90AB1HSP90B1ADORA2A | |
| SCHEMBL14494933 | 0.83 | HSP90AA1 (0.72) | ERBB2HSP90AA1HSP90AB1HSP90B1ADORA2A | |
| SCHEMBL1965080 | 0.83 | HSP90AA1 (0.72) | ERBB2HSP90AA1HSP90AB1HSP90B1ADORA2A | |
| SCHEMBL1963233 | 0.83 | HSP90AA1 (0.78) | ERBB2HSP90AA1HSP90AB1HSP90B1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129334-A1 | Orally Active Purine-Based Inhibitors of Heat Shock Protein 90 | CONFORMA THERAPEUTICS CORPORATION (US) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129334-A1 | Orally Active Purine-Based Inhibitors of Heat Shock Protein 90 | HSP90AB1, HSP90AA1, HSP90AB2P | ERBB2 1609/4885HSP90AA1 2/4885HSP90AB1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.