Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.34 |
| ▸ | DHFR | P00374 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HK1 | P19367 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2995160 | 0.77 | ADORA2A (0.35) | HSP90AA1HSP90AB1ADORA2ACYP1A2DHFR | |
| SCHEMBL2991768 | 0.76 | ADORA2A (0.34) | HSP90AA1HSP90AB1ADORA2ACYP1A2DHFR | |
| SCHEMBL2991772 | 0.75 | ADORA2A (0.35) | HSP90AA1HSP90AB1ADORA2ACYP1A2DHFR | |
| SCHEMBL2995163 | 0.75 | ADORA2A (0.35) | HSP90AA1HSP90AB1ADORA2ACYP1A2DHFR | |
| SCHEMBL3000654 | 0.74 | HSP90AA1 (0.35) | HSP90AA1HSP90AB1ADORA2ACYP1A2DHFR | |
| SCHEMBL3290187 | 0.73 | HSP90AA1 (0.33) | HSP90AA1HSP90AB1ADORA2ACYP1A2DHFR | |
| SCHEMBL6838428 | 0.72 | NSD3 (0.40) | HSP90AA1HSP90AB1ADORA2ACYP1A2DHFR | |
| SCHEMBL2912064 | 0.72 | ADORA2A (0.47) | HSP90AA1HSP90AB1ADORA2ACYP1A2DHFR | |
| SCHEMBL15532125 | 0.71 | NSD3 (0.40) | HSP90AA1HSP90AB1ADORA2ACYP1A2DHFR | |
| SCHEMBL6837777 | 0.71 | NSD3 (0.40) | HSP90AA1HSP90AB1ADORA2ACYP1A2DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157448-B2 | Acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | LG LIFE SCIENCES LTD. (KR) | 2007-01-02 | — | — | US | disclosed |
| US-20040063668-A1 | Novel acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | LG LIFE SCIENCES LTD. (KR) | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063668-A1 | Novel acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | PNP, ITPA, MTAP | HSP90AA1 4081/4885HSP90AB1 3304/4885ADORA2A 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.