Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | OGA | O60502 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4710443 | 1.00 | MAPT (0.47) | MAPTSMN1; SMN2HIF1AACACBUTS2R | |
| SCHEMBL4709595 | 1.00 | MAPT (0.47) | MAPTSMN1; SMN2HIF1AACACBUTS2R | |
| SCHEMBL4708524 | 0.88 | SMN1; SMN2 (0.46) | MAPTSMN1; SMN2HIF1AACACBUTS2R | |
| SCHEMBL5849758 | 0.88 | SMN1; SMN2 (0.46) | MAPTSMN1; SMN2HIF1AACACBUTS2R | |
| SCHEMBL14453013 | 0.88 | SMN1; SMN2 (0.46) | MAPTSMN1; SMN2HIF1AACACBUTS2R | |
| SCHEMBL4712906 | 0.87 | HIF1A (0.49) | MAPTSMN1; SMN2HIF1AUTS2RTSHR | |
| SCHEMBL4709503 | 0.87 | HIF1A (0.49) | MAPTSMN1; SMN2HIF1AUTS2RTSHR | |
| SCHEMBL4708914 | 0.84 | MAPT (0.40) | MAPTSMN1; SMN2HIF1AACACBUTS2R | |
| SCHEMBL4708912 | 0.84 | MAPT (0.40) | MAPTSMN1; SMN2HIF1AACACBUTS2R | |
| SCHEMBL4712115 | 0.82 | OGA (0.48) | MAPTSMN1; SMN2OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241765-B2 | Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues | NEUROGEN CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241765-B2 | Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues | NEUROGEN CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241765-B2 | Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues | NEUROGEN CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |