Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2843678 | 0.83 | CYP2C9 (0.50) | CYP3A4CYP2C9CYP2C19KCNH2CACNA1C | |
| SCHEMBL2843904 | 0.81 | CACNA1C (0.54) | CACNA1C | |
| SCHEMBL2843902 | 0.81 | CYP2C9 (0.47) | CYP3A4CYP2C9CYP2C19KCNH2CACNA1C | |
| SCHEMBL17464359 | 0.81 | CYP3A4 (0.45) | CYP3A4CYP2C9CYP2C19KCNH2CYP2C8 | |
| SCHEMBL2837312 | 0.80 | CYP3A4 (0.43) | CYP3A4CYP2C9CYP2C19KCNH2CYP2C8 | |
| SCHEMBL17464372 | 0.80 | CYP3A4 (0.49) | CYP3A4CYP2C9CYP2C19KCNH2CYP2C8 | |
| SCHEMBL2845753 | 0.79 | CYP3A4 (0.54) | CYP3A4CYP2C9CYP2C19KCNH2 | |
| SCHEMBL16112947 | 0.78 | CYP2C9 (0.47) | CYP3A4CYP2C9CYP2C19KCNH2CYP2C8 | |
| SCHEMBL2845474 | 0.78 | CYP3A4 (0.42) | CYP3A4CYP2C9CYP2C19KCNH2CYP2C8 | |
| SCHEMBL2839625 | 0.78 | CYP3A4 (0.54) | CYP3A4CYP2C9CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265152-B2 | Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases | VIROPHARMA INCORPORATED (US) | 2007-09-04 | — | — | US | claimed |