Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2504913 | 1.00 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL3378397 | 0.84 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL3453014 | 0.84 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL2498667 | 0.82 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL3721902 | 0.81 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL2360997 | 0.81 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL3721907 | 0.81 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL3111386 | 0.81 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL2325928 | 0.80 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL2332009 | 0.80 | KCNH2 (0.45) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799676-A2 | NEW BICYCLIC ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006032466-A2 | NEW BICYCLIC ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-03-30 | — | — | WO | disclosed |