Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.95 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5527774 | 1.00 | PTGDR2 (0.95) | PTGDR2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL2085880 | 0.97 | PTGDR2 (1.00) | PTGDR2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL2085879 | 0.97 | PTGDR2 (1.00) | PTGDR2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL2088772 | 0.94 | PTGDR2 (0.82) | PTGDR2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL2088768 | 0.94 | PTGDR2 (0.82) | PTGDR2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL2086564 | 0.92 | PTGDR2 (0.89) | PTGDR2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL2088718 | 0.89 | PTGDR2 (0.83) | PTGDR2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL2088715 | 0.89 | PTGDR2 (0.83) | PTGDR2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL2087358 | 0.88 | PTGDR2 (0.91) | PTGDR2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL2087355 | 0.88 | PTGDR2 (0.91) | PTGDR2MEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740171-A1 | INDOL-1-YL-ACETIC ACID DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2007-01-10 | — | — | EP | claimed |
| WO-2005094816-A1 | INDOL-1-YL-ACETIC ACID DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2005-10-13 | — | — | WO | claimed |
| EP-1740171-A1 | INDOL-1-YL-ACETIC ACID DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005094816-A1 | INDOL-1-YL-ACETIC ACID DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2005-10-13 | — | — | WO | disclosed |