Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.50 |
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | HTR2B | P41595 | 4/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5375816 | 0.92 | TLR7 (0.44) | TLR7HTR2AHTR2BPDE4DPOLB | |
| Water SCHEMBL5343392 | 0.91 | TLR7 (0.43) | TLR7HTR2AHTR2BPDE4DPOLB | |
| Epetirimod SCHEMBL29454521 | 0.84 | TLR7 (0.70) | TLR7HTR2AHTR2BPDE4DPOLB | |
| Epetirimod SCHEMBL544542 | 0.84 | TLR7 (0.70) | TLR7HTR2AHTR2BPDE4DPOLB | |
| Epetirimod SCHEMBL29350668 | 0.84 | TLR7 (0.70) | TLR7HTR2AHTR2BPDE4DPOLB | |
| SCHEMBL4562038 | 0.83 | TLR7 (0.72) | TLR7HTR2AHTR2BPDE4DPOLB | |
| SCHEMBL4085639 | 0.82 | TLR7 (0.48) | TLR7HTR2AHTR2BPDE4DPOLB | |
| Epetirimod SCHEMBL4985288 | 0.77 | TLR7 (0.61) | TLR7HTR2AHTR2BPDE4DPOLB | |
| Epetirimod SCHEMBL4178900 | 0.77 | TLR7 (0.61) | TLR7HTR2AHTR2BPDE4DPOLB | |
| SCHEMBL3350693 | 0.77 | TLR7 (0.47) | TLR7HTR2AHTR2BPDE4DPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845980-A2 | AQUEOUS GEL FORMULATIONS CONTAINING 1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C][1,5]NAPHTHYRIDIN-4-AMINE | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | claimed |
| WO-2006084073-A2 | AQUEOUS GEL FORMULATIONS CONTAINING 1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C][1,5]NAPHTHYRIDIN-4-AMINE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-08-10 | — | — | WO | claimed |