SCHEMBL5528378

SCHEMBL5528378

C#Cc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(N=CN3CCC(C(=O)O)CC3)cc2F)nc1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 18/20 0.51
KCNH2 Q12809 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5538276 0.94 F10 (0.51) F10KCNH2
SCHEMBL5532854 0.94 F10 (0.51) F10KCNH2
SCHEMBL5531842 0.90 F10 (0.61) F10KCNH2
SCHEMBL5528366 0.90 F10 (0.55) F10KCNH2
SCHEMBL5534223 0.89 F10 (0.48) F10KCNH2
SCHEMBL5533872 0.89 F10 (0.45) F10
SCHEMBL5534833 0.88 F10 (0.51) F10KCNH2
SCHEMBL5533458 0.86 F10 (0.46) F10KCNH2
SCHEMBL5541001 0.84 F10 (0.61) F10KCNH2
SCHEMBL5535968 0.84 F10 (0.55) F10KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1373194-B1 BENZAMIDE INHIBITORS OF FACTOR Xa MILLENNIUM PHARM INC (US) 2007-08-01 EP claimed