SCHEMBL5528823

SCHEMBL5528823

CCCCC(=CN)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.44
CES2 O00748 1/20 0.44
APEX1 P27695 1/20 0.42
GRIK1 P39086 1/20 0.42
ALDH1A1 P00352 3/20 0.41
AKR1B1 P15121 1/20 0.41
TP53 P04637 1/20 0.41
ALOX15 P16050 2/20 0.40
GPR84 Q9NQS5 7/20 0.39
PPARG P37231 6/20 0.39
PPARD Q03181 6/20 0.39
PPARA Q07869 6/20 0.39
HDAC11 Q96DB2 5/20 0.39
TSHR P16473 4/20 0.39
TLR2 O60603 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
FABP4 P15090 2/20 0.39
PTPN1 P18031 2/20 0.39
SLC22A6 Q4U2R8 1/20 0.39
SLC22A8 Q8TCC7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7657118 0.93 AKR1B1 (0.50) CES1CES2APEX1ALDH1A1AKR1B1
SCHEMBL7657108 0.93 AKR1B1 (0.50) CES1CES2APEX1ALDH1A1AKR1B1
SCHEMBL13912574 0.86
SCHEMBL9506327 0.86
SCHEMBL20163589 0.82 CES1 (0.44) CES1CES2ALDH1A1AKR1B1TP53
SCHEMBL88045 0.81 CES1 (0.48) CES1CES2APEX1ALDH1A1AKR1B1
SCHEMBL1287562 0.81 CES1 (0.48) CES1CES2APEX1ALDH1A1AKR1B1
SCHEMBL3344502 0.81 CES1 (0.48) CES1CES2APEX1ALDH1A1AKR1B1
SCHEMBL481537 0.81 CES1 (0.48) CES1CES2APEX1ALDH1A1AKR1B1
SCHEMBL8089512 0.81 CES1 (0.48) CES1CES2APEX1ALDH1A1AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0964052-B1 Use of nitrogen-containing ethylene copolymers for producing fuel oils with improved lubricating activity CLARIANT GMBH (DE) 2004-02-04 EP claimed
EP-0964052-A1 Use of nitrogen-containing ethylene copolymers for producing fuel oils with improved lubricating activity Clariant GmbH (DE) 1999-12-15 EP claimed
EP-1749873-B1 ADDITIVES AND THEIR USE FOR IMPROVING THE ELECTRICAL CONDUCTIVITY AND COLD FLOWABILITY OF MINERAL OIL DISTILLATES CLARIANT PRODUKTE DEUTSCHLAND (DE) 2018-04-04 EP disclosed
EP-1749873-A2 Mineral oils with improved conductivity and cold flowability. Clariant Produkte (Deutschland) GmbH (DE) 2007-02-07 EP disclosed
EP-1134274-B1 Use of carboxylic acids and derivatives thereof as solvent for hydroxyl groups carrying polymers CLARIANT PRODUKTE DEUTSCHLAND (DE) 2006-11-29 EP disclosed
EP-1134273-B1 Use of carboxylic acids and derivatives thereof as solvent for hydroxyl groups carrying polymers CLARIANT PRODUKTE DEUTSCHLAND (DE) 2006-11-02 EP disclosed
EP-1200539-B1 USE OF HYDROXYL GROUP-CONTAINING COPOLYMERS FOR PRODUCING FUEL OILS WITH IMPROVED LUBRICITY CLARIANT GMBH (DE) 2004-10-27 EP disclosed
EP-0964052-B1 Use of nitrogen-containing ethylene copolymers for producing fuel oils with improved lubricating activity CLARIANT GMBH (DE) 2004-02-04 EP disclosed
EP-1200539-A1 USE OF HYDROXYL GROUP-CONTAINING COPOLYMERS FOR PRODUCING FUEL OILS WITH IMPROVED LUBRICITY Clariant GmbH (DE) 2002-05-02 EP disclosed
EP-1134273-A2 Blends of carboxylic acids, derivatives thereof and hydroxyl groups carrying polymers, and use thereof to improve the lubricating activity of oils Clariant GmbH (DE) 2001-09-19 EP disclosed
EP-1134274-A2 Blends of carboxylic acids, derivatives thereof and hydroxyl groups carrying polymers, and use thereof to improve the lubricating activity of oils Clariant GmbH (DE) 2001-09-19 EP disclosed
WO-2000078897-A1 USE OF HYDROXYL GROUP-CONTAINING COPOLYMERS FOR PRODUCING FUEL OILS WITH IMPROVED LUBRICITY CLARIANT GMBH (DE) 2000-12-28 WO disclosed
EP-0964052-A1 Use of nitrogen-containing ethylene copolymers for producing fuel oils with improved lubricating activity Clariant GmbH (DE) 1999-12-15 EP disclosed
EP-0721475-B1 ETHYLENE-BASED COPOLYMERS AND THEIR USE AS VISCOSITY IMPROVERS IN PETROLEUM DISTILLATES BASF AG (DE) 1997-04-23 EP disclosed
EP-0721475-A1 ETHYLENE-BASED COPOLYMERS AND THEIR USE AS VISCOSITY IMPROVERS IN PETROLEUM DISTILLATES BASF AG (DE) 1996-07-17 EP disclosed
WO-1995009877-A1 ETHYLENE-BASED COPOLYMERS AND THEIR USE AS VISCOSITY IMPROVERS IN PETROLEUM DISTILLATES BASF AKTIENGESELLSCHAFT (DE) 1995-04-13 WO disclosed