Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 6/20 | 0.34 |
| ▸ | EDNRB | P24530 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4765080 | 0.94 | EDNRA (0.37) | EDNRAEDNRBAGTR1 | |
| SCHEMBL5531222 | 0.89 | EDNRA (0.36) | EDNRAEDNRBAGTR1 | |
| SCHEMBL4774738 | 0.88 | EDNRA (0.36) | EDNRAEDNRB | |
| SCHEMBL5529066 | 0.87 | EDNRA (0.35) | EDNRAAGTR1 | |
| SCHEMBL5531007 | 0.86 | EDNRA (0.41) | EDNRAEDNRBAGTR1 | |
| SCHEMBL4770734 | 0.86 | EDNRA (0.35) | EDNRAEDNRB | |
| SCHEMBL4769082 | 0.84 | EDNRA (0.38) | EDNRAAGTR1 | |
| SCHEMBL4765035 | 0.84 | EDNRA (0.33) | EDNRAEDNRB | |
| SCHEMBL4774155 | 0.84 | EDNRA (0.34) | EDNRAEDNRB | |
| SCHEMBL4771379 | 0.82 | EDNRA (0.34) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1741713-A2 | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists | Bristol-Myers Squibb Company (US) | 2007-01-10 | — | — | EP | disclosed |