SCHEMBL5529352

SCHEMBL5529352

Clc1ccc(Cc2nnoc2CCc2c[nH]cn2)cc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSP90AB1 P08238 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL224352 0.76 DAO (0.41) LMNA
SCHEMBL11047959 0.74 HSP90AB1 (0.47) HSP90AB1LMNA
Gr-175737 SCHEMBL195040 0.72 MAPT (0.49)
SCHEMBL9034160 0.69 MAOB (0.40) LMNA
SCHEMBL2240994 0.68 HRH3 (0.49)
SCHEMBL9078573 0.67 HSP90AB1 (0.41) HSP90AB1LMNA
SCHEMBL7971701 0.67 HRH3 (0.40) LMNA
SCHEMBL6179255 0.66 CHRM2 (0.47)
SCHEMBL9079880 0.66 HCAR2 (0.40) LMNA
SCHEMBL647818 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070202050-A1 Pharmaceutical Formulations SCHERING CORPORATION 2007-08-30 US disclosed