Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CNR1 | P21554 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13996993 | 0.89 | KDM4E (0.76) | KDM4EEPHX1KMT2AEPHX2RAB9A | |
| SCHEMBL15093821 | 0.81 | EPHX2 (0.86) | KDM4EEPHX1KMT2AEPHX2RAB9A | |
| SCHEMBL17117239 | 0.80 | KMT2A (0.65) | KDM4EEPHX1KMT2AEPHX2RAB9A | |
| SCHEMBL12196188 | 0.80 | EPHX1 (1.00) | KDM4EEPHX1HDAC1KMT2AEPHX2 | |
| SCHEMBL2109520 | 0.79 | HDAC1 (1.00) | HDAC1RAB9ASMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL17117232 | 0.79 | KMT2A (0.64) | KDM4EEPHX1KMT2AEPHX2RAB9A | |
| SCHEMBL21045504 | 0.78 | KMT2A (1.00) | KDM4EEPHX1KMT2ARAB9AALDH1A1 | |
| SCHEMBL10363534 | 0.78 | KDM4E (0.71) | KDM4EEPHX1KMT2ARAB9AALDH1A1 | |
| SCHEMBL3383335 | 0.78 | HDAC1 (0.71) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL10588979 | 0.78 | EPHX2 (0.70) | KDM4EEPHX1KMT2AEPHX2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753861-A2 | FRUCTOSEAMINE 3 KINASE AND THE FORMATION OF COLLAGEN AND ELASTIN | Dynamis Therapeutics, Inc. (US) | 2007-02-21 | — | — | EP | claimed |
| WO-2005079463-A2 | FRUCTOSEAMINE 3 KINASE AND THE FORMATION OF COLLAGEN AND ELASTIN | DYNAMIS THERAPEUTICS, INC. (US) | 2005-09-01 | — | — | WO | claimed |