Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 20/20 | 0.76 |
| ▸ | CHUK | O15111 | 6/20 | 0.64 |
| ▸ | BTK | Q06187 | 2/20 | 0.64 |
| ▸ | AURKA | O14965 | 1/20 | 0.64 |
| ▸ | FLT3 | P36888 | 1/20 | 0.64 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.64 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3798002 | 0.89 | IKBKB (0.78) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL3795647 | 0.88 | IKBKB (0.91) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL3795649 | 0.88 | IKBKB (0.91) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL3795814 | 0.87 | IKBKB (1.00) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL3797615 | 0.86 | IKBKB (0.98) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL5786506 | 0.86 | IKBKB (0.66) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL3800722 | 0.85 | IKBKB (0.88) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL3800652 | 0.83 | IKBKB (0.71) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL3798387 | 0.82 | IKBKB (0.78) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL3797614 | 0.82 | IKBKB (0.76) | IKBKBCHUKBTKAURKAFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1793826-A2 | CHEMICAL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2007-06-13 | — | — | EP | claimed |
| WO-2006034317-A2 | CHEMICAL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2006-03-30 | — | — | WO | claimed |
| EP-1793826-A2 | CHEMICAL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006034317-A2 | CHEMICAL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2006-03-30 | — | — | WO | disclosed |