Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5531799 | 0.94 | F10 (0.46) | F10ABCB1ABCC1KCNH2F2 | |
| SCHEMBL5532509 | 0.93 | F10 (0.47) | F10ABCB1ABCC1KCNH2F2 | |
| SCHEMBL5541061 | 0.92 | F10 (0.46) | F10ABCB1ABCC1KCNH2F2 | |
| SCHEMBL5530794 | 0.92 | F10 (0.56) | F10KCNH2F2 | |
| SCHEMBL7132134 | 0.83 | F10 (0.44) | F10ABCB1ABCC1KCNH2FGFR3 | |
| SCHEMBL5532539 | 0.79 | F10 (0.53) | F10ABCC1F2 | |
| SCHEMBL14345374 | 0.79 | F10 (0.54) | F10KCNH2F2 | |
| SCHEMBL14345182 | 0.79 | F10 (0.68) | F10KCNH2F2 | |
| SCHEMBL5534784 | 0.77 | F10 (0.62) | F10KCNH2F2 | |
| SCHEMBL5534121 | 0.75 | ABCB1 (0.37) | F10ABCB1ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373194-B1 | BENZAMIDE INHIBITORS OF FACTOR Xa | MILLENNIUM PHARM INC (US) | 2007-08-01 | — | — | EP | claimed |
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| EP-1373194-A1 | BENZAMIDE INHIBITORS OF FACTOR Xa | Millennium Pharmaceuticals, Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002079145-A1 | BENZAMIDE INHIBITORS OF FACTOR Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-10-10 | — | — | WO | disclosed |