Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13233232 | 0.83 | AKT1 (1.00) | AKT1AKT2 | |
| SCHEMBL2896545 | 0.83 | AKT1 (0.78) | AKT1AKT2 | |
| SCHEMBL2894176 | 0.82 | AKT1 (1.00) | AKT1AKT2 | |
| SCHEMBL1939574 | 0.81 | AKT1 (1.00) | AKT1AKT2 | |
| SCHEMBL2899272 | 0.80 | AKT1 (1.00) | AKT1AKT2 | |
| SCHEMBL2898522 | 0.80 | AKT1 (1.00) | AKT1AKT2 | |
| SCHEMBL2938104 | 0.80 | AKT1 (0.71) | AKT1AKT2 | |
| SCHEMBL2899088 | 0.79 | AKT1 (0.74) | AKT1AKT2 | |
| SCHEMBL2897899 | 0.79 | AKT1 (0.82) | AKT1AKT2 | |
| SCHEMBL2898860 | 0.78 | AKT1 (0.73) | AKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737861-A1 | INHIBITORS OF AKT ACTIVITY | Merck & Co., Inc. (US) | 2007-01-03 | — | — | EP | claimed |
| WO-2005100356-A1 | INHIBITORS OF AKT ACTIVITY | MERCK & CO., INC. (US) | 2005-10-27 | — | — | WO | claimed |
| EP-1737861-A1 | INHIBITORS OF AKT ACTIVITY | Merck & Co., Inc. (US) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005100356-A1 | INHIBITORS OF AKT ACTIVITY | MERCK & CO., INC. (US) | 2005-10-27 | — | — | WO | disclosed |