Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.53 |
| ▸ | AXL | P30530 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.51 |
| ▸ | KMO | O15229 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | TEK | Q02763 | 1/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12373165 | 0.95 | CYP19A1 (0.54) | CYP19A1CYP2A6ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL5527335 | 0.94 | CYP2A6 (0.60) | CYP19A1CYP2A6ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL18134287 | 0.91 | CYP19A1 (0.66) | CYP19A1CYP2A6ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL5531183 | 0.91 | CYP19A1 (0.66) | CYP19A1CYP2A6ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL18134293 | 0.91 | CYP19A1 (0.66) | CYP19A1CYP2A6ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL24493204 | 0.91 | CYP19A1 (0.66) | CYP19A1CYP2A6ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL18650174 | 0.91 | CYP19A1 (0.66) | CYP19A1CYP2A6ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL18134279 | 0.91 | CYP19A1 (0.66) | CYP19A1CYP2A6ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL21396881 | 0.91 | CYP19A1 (0.66) | CYP19A1CYP2A6ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL24492828 | 0.91 | CYP19A1 (0.66) | CYP19A1CYP2A6ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865905-B2 | Organic compounds | GENERAL ELECTRIC COMPANY (US) | 2014-10-21 | — | — | US | disclosed |
| US-20130217882-A1 | ORGANIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2013-08-22 | — | — | US | disclosed |
| US-8426601-B2 | Process for making organic compounds and the organic compounds made therefrom | GENERAL ELECTRIC COMPANY (US) | 2013-04-23 | — | — | US | disclosed |
| US-20120178938-A1 | PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2012-07-12 | — | — | US | disclosed |
| US-8178682-B2 | Process for making organic compounds and the organic compounds made therefrom | GENERAL ELECTRIC COMPANY (US) | 2012-05-15 | — | — | US | disclosed |
| US-20100331547-A1 | PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331547-A1 | PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM | CYP4F11, BCL6, CYP2F1 | CYP19A1 130/4885CYP2A6 41/4885ALDH1A1 2404/4885 |
| US-20120178938-A1 | PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM | CYP2F1, CYP4F2, CYP1B1 | CYP19A1 143/4885CYP2A6 30/4885ALDH1A1 583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.