Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.31 |
| ▸ | ACP1 | P24666 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5536648 | 0.93 | F10 (0.38) | F10TRPV1FAAHMEN1NPC1 | |
| SCHEMBL5510376 | 0.89 | F10 (0.38) | F10TRPV1FAAHMEN1NPC1 | |
| SCHEMBL4558647 | 0.89 | F10 (0.38) | F10MEN1ALDH1A1MAPTHTT | |
| SCHEMBL5508680 | 0.86 | F10 (0.35) | F10TRPV1FAAH | |
| SCHEMBL5513576 | 0.84 | F10 (0.37) | F10TRPV1FAAHMEN1NPC1 | |
| SCHEMBL4458588 | 0.82 | F10 (0.41) | F10 | |
| SCHEMBL5527807 | 0.82 | TRPV1 (0.41) | F10TRPV1FAAHMEN1NPC1 | |
| SCHEMBL5526021 | 0.82 | TRPV1 (0.39) | F10TRPV1FAAHMEN1NPC1 | |
| SCHEMBL4558759 | 0.81 | F10 (0.44) | F10MEN1NPC1ALDH1A1LMNA | |
| SCHEMBL5530339 | 0.81 | F10 (0.39) | F10TRPV1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747217-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005111029-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |