Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.38 |
| ▸ | GRK6 | P43250 | 2/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2948145 | 0.88 | PPARD (0.51) | PPARDPPARA | |
| SCHEMBL2946664 | 0.79 | PPARD (0.49) | PPARDPPARA | |
| SCHEMBL2948370 | 0.76 | PPARD (0.49) | PPARDPPARA | |
| SCHEMBL2946652 | 0.75 | PPARD (0.58) | PPARDPPARA | |
| SCHEMBL2948560 | 0.75 | PPARD (0.58) | PPARDPPARA | |
| SCHEMBL2941706 | 0.75 | PPARD (0.51) | PPARDGRK6PPARA | |
| SCHEMBL2941998 | 0.75 | PPARD (0.60) | PPARDPPARA | |
| SCHEMBL2944584 | 0.68 | PPARD (0.54) | PPARDPPARA | |
| SCHEMBL2946740 | 0.68 | PPARD (0.41) | PPARDPPARA | |
| SCHEMBL2946595 | 0.67 | PTGDR (0.40) | PPARDPTGDRPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1843763-A2 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM, LLC (BM) | 2007-10-17 | — | — | EP | claimed |
| WO-2006084176-A2 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2006-08-10 | — | — | WO | claimed |