SCHEMBL5534227

SCHEMBL5534227

C#Cc1ccc(NC(=O)c2[c]ccc(-c3ccc(C(=N)N(C)C)cc3)c2)nc1

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.57
KCNH2 Q12809 2/20 0.43
F2 P00734 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5534784 0.81 F10 (0.62) F10KCNH2F2
SCHEMBL5530794 0.74 F10 (0.56) F10KCNH2F2
SCHEMBL14345402 0.74 F10 (0.76) F10KCNH2F2
SCHEMBL14345164 0.73 F10 (1.00) F10KCNH2F2
SCHEMBL14345275 0.72 F10 (0.77) F10KCNH2F2
SCHEMBL5532203 0.71 F10 (0.51) F10KCNH2F2
SCHEMBL14345370 0.70 F10 (0.62) F10KCNH2F2
SCHEMBL14345083 0.70 F10 (0.81) F10KCNH2F2
SCHEMBL14345345 0.69 F10 (0.86) F10KCNH2F2
SCHEMBL14345266 0.68 F10 (0.82) F10KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1373194-B1 BENZAMIDE INHIBITORS OF FACTOR Xa MILLENNIUM PHARM INC (US) 2007-08-01 EP claimed