⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL867084 | 0.83 | — | — | |
| SCHEMBL7033361 | 0.82 | — | — | |
| Methoxymethane SCHEMBL10627012 | 0.79 | CHRM2 (0.31) | — | |
| SCHEMBL26690010 | 0.77 | — | — | |
| Methyl Alcohol SCHEMBL28712278 | 0.71 | — | — | |
| SCHEMBL1773637 | 0.71 | — | — | |
| SCHEMBL5077086 | 0.71 | — | — | |
| SCHEMBL1792611 | 0.71 | — | — | |
| SCHEMBL7037811 | 0.71 | — | — | |
| SCHEMBL3138781 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8283454-B2 | Processes for the preparation of SGLT2 inhibitors | THERACOS, INC. (US) | 2012-10-09 | — | — | US | claimed |
| JP-5025105-A | — | — | None | — | — | JP | disclosed |
| CN-115427035-B | ENL/AF9 YEATS inhibitors | 洛克菲勒大学 | 2025-04-22 | — | — | CN | disclosed |
| US-20230027198-A1 | INHIBITORS OF ENL/AF9 YEATS | THE ROCKEFELLER UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
| CN-115427035-A | ENL/AF9YEATS inhibitors | 洛克菲勒大学 | 2022-12-02 | — | — | CN | disclosed |
| EP-4076440-A1 | INHIBITORS OF ENL/AF9 YEATS | The Rockefeller University (US) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021127166-A1 | INHIBITORS OF ENL/AF9 YEATS | THE ROCKEFELLER UNIVERSITY (US) | 2021-06-24 | — | — | WO | disclosed |
| EP-3016934-B1 | HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF SUMO ACTIVATING ENZYME | MILLENNIUM PHARM INC (US) | 2018-01-10 | — | — | EP | disclosed |
| US-9695154-B2 | Heteroaryl inhibitors of sumo activating enzyme | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-9695154-B2 | Heteroaryl inhibitors of sumo activating enzyme | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-6645396-B2 | A hydrogen getter formulation containing an unsaturated organic triazine compound or dimeric or polymeric triazine and a hydrogenation catalyst | SAES GETTERS S.P.A. (IT) | 2003-11-11 | — | — | US | disclosed |
| US-20030087920-A1 | Butyne diol derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2003-05-08 | — | — | US | disclosed |
| US-20030065117-A1 | Modified silicone compound, process of producing the same, and cured object obtained therefrom | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2003-04-03 | — | — | US | disclosed |
| US-20030052304-A1 | Hydrogen getter composition | SAES GETTERS S.P.A. | 2003-03-20 | — | — | US | disclosed |
| EP-1265810-A1 | HYDROGEN GETTER COMPOSITION | SAES GETTERS S.p.A. (IT) | 2002-12-18 | — | — | EP | disclosed |
| EP-1244637-A1 | BUTYNE DIOL DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001068516-A1 | HYDROGEN GETTER COMPOSITION | SAES GETTERS S.P.A. (IT) | 2001-09-20 | — | — | WO | disclosed |
| WO-2001046156-A1 | BUTYNE DIOL DERIVATIVES | ACTELION PHARMACEUTICALS LTD. (CH) | 2001-06-28 | — | — | WO | disclosed |
| JP-H0525105-A | N-METHOXYBUTYNYLANILINE DERIVATIVE AND ITS PRODUCTION | CENTRAL GLASS CO LTD | 1993-02-02 | — | — | JP | disclosed |
| US-4218372-A | Azo compounds having a β-alkynyloxy carbonylalkyl group on the coupling component radical | SANDOZ LTD. (CH) | 1980-08-19 | — | — | US | disclosed |