Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 18/20 | 0.79 |
| ▸ | CYP2D6 | P10635 | 12/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.79 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.57 |
| ▸ | GSK3A | P49840 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81558 | 1.00 | GSK3B (0.79) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL88164 | 0.91 | GSK3B (0.80) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL87674 | 0.91 | GSK3B (0.85) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL84001 | 0.90 | GSK3B (0.81) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL88183 | 0.90 | GSK3B (0.84) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL87722 | 0.90 | GSK3B (0.84) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL88433 | 0.89 | GSK3B (0.82) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL82880 | 0.89 | GSK3B (0.82) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL87770 | 0.89 | GSK3B (0.81) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL88036 | 0.88 | GSK3B (1.00) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805164-A2 | 6-(PYRIDINYL)-4-PYRIMIDONE DERIVATES AS TAU PROTEIN KINASE 1 INHIBITORS | Mitsubishi Pharma Corporation (JP) | 2007-07-11 | — | — | EP | claimed |
| WO-2006036015-A2 | 6- (PYRIDINYL) -4-PYRIMIDONE DERIVATES AS TAU PROTEIN KINASE 1 INHIBITORS | MITSUBISHI PHARMA CORPORATION (JP) | 2006-04-06 | — | — | WO | claimed |