SCHEMBL5535320

SCHEMBL5535320

CC(O)CCCCS(=O)(=O)O

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.42
TP53 P04637 1/20 0.39
PTGS1 P23219 1/20 0.35
PDE4A P27815 1/20 0.35
LMNA P02545 1/20 0.35
SLC6A6 P31641 1/20 0.35
CYP2C19 P33261 1/20 0.35
BLM P54132 1/20 0.35
ALDH1A1 P00352 2/20 0.34
MAPT P10636 1/20 0.34
EPHX2 P34913 1/20 0.33
TRPV1 Q8NER1 1/20 0.31
TRPA1 O75762 1/20 0.31
S1PR2 O95136 1/20 0.30
S1PR1 P21453 1/20 0.30
S1PR3 Q99500 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11784499 0.98 APP (0.41) APPTP53PTGS1PDE4ALMNA
SCHEMBL16370305 0.98 APP (0.41) APPTP53PTGS1PDE4ALMNA
SCHEMBL25385302 0.93 APP (0.44) APPTP53PTGS1PDE4ALMNA
SCHEMBL25382857 0.93 APP (0.44) APPTP53PTGS1PDE4ALMNA
SCHEMBL5144485 0.93 APP (0.44) APPTP53PTGS1PDE4ALMNA
SCHEMBL5637565 0.83 APP (0.44) APPTP53PTGS1PDE4ALMNA
SCHEMBL5026578 0.82
SCHEMBL918218 0.81 APP (0.35) APPALDH1A1EPHX2
SCHEMBL25355943 0.81 APP (0.42) APPTP53PTGS1PDE4ALMNA
SCHEMBL9011748 0.81 APP (0.42) APPTP53PTGS1PDE4ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160133992-A1 DRYING OF ELECTROLYTE MIXTURES CONTAINING ACIDS WITH MOLECULAR SIEVES BASF SE (DE) 2016-05-12 US claimed
WO-2015004236-A1 DRYING OF ELECTROLYTE MIXTURES CONTAINING ACIDS WITH MOLECULAR SIEVES BASF SE (DE) 2015-01-15 WO claimed
US-20050048000-A1 Amyloid targeting imaging agents and uses thereof NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2005-03-03 US claimed
US-20020115717-A1 Amyloid targeting imaging agents and uses thereof NEUROCHEM (INTERNATIONAL) LIMITED (GI) 2002-08-22 US claimed
US-10230131-B2 Method for producing a dehydrated liquid organic carbonate mixture Gotion Inc. (US) 2019-03-12 US disclosed
US-20160218391-A1 METHOD FOR PRODUCING A DEHYDRATED LIQUID ORGANIC CARBONATE MIXTURE BASF SE (DE) 2016-07-28 US disclosed
US-20160133992-A1 DRYING OF ELECTROLYTE MIXTURES CONTAINING ACIDS WITH MOLECULAR SIEVES BASF SE (DE) 2016-05-12 US disclosed
WO-2015004233-A1 METHOD FOR PRODUCING A DEHYDRATED LIQUID ORGANIC CARBONATE MIXTURE BASF SE (DE) 2015-01-15 WO disclosed
WO-2015004236-A1 DRYING OF ELECTROLYTE MIXTURES CONTAINING ACIDS WITH MOLECULAR SIEVES BASF SE (DE) 2015-01-15 WO disclosed
US-7311893-B2 Amyloid targeting imaging agents and uses thereof NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2007-12-25 US disclosed
US-20050048000-A1 Amyloid targeting imaging agents and uses thereof NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2005-03-03 US disclosed
EP-1303311-A2 AMYLOID TARGETING IMAGING AGENTS AND USES THEREOF Neurochem, Inc. (CA) 2003-04-23 EP disclosed
US-20020115717-A1 Amyloid targeting imaging agents and uses thereof NEUROCHEM (INTERNATIONAL) LIMITED (GI) 2002-08-22 US disclosed
WO-2002007781-A2 AMYLOID TARGETING IMAGING AGENTS AND USES THEREOF NEUROCHEM INC. (CA) 2002-01-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050048000-A1 Amyloid targeting imaging agents and uses thereof APP, APBA1, BACE1 APP 1/4885TP53 721/4885PTGS1 4215/4885
US-20020115717-A1 Amyloid targeting imaging agents and uses thereof APP, APBA1, BACE1 APP 1/4885TP53 721/4885PTGS1 4215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.