Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 10/20 | 0.53 |
| ▸ | PPARG | P37231 | 8/20 | 0.36 |
| ▸ | PPARD | Q03181 | 7/20 | 0.36 |
| ▸ | PPARA | Q07869 | 6/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1993438 | 0.92 | GRM2 (0.61) | GRM2PPARGPPARDPPARACYP4F2 | |
| SCHEMBL12614656 | 0.81 | GRM2 (0.47) | GRM2PPARGPPARDPPARACYP4F2 | |
| SCHEMBL1995238 | 0.81 | GRM2 (0.68) | GRM2PPARGPPARDPPARA | |
| SCHEMBL1997138 | 0.80 | GRM2 (0.65) | GRM2PPARGPPARDPPARACYP4F2 | |
| SCHEMBL1997237 | 0.78 | GRM2 (0.71) | GRM2PPARGPPARDPPARA | |
| SCHEMBL1996315 | 0.78 | GRM2 (0.65) | GRM2PPARGPPARDPPARACYP4F2 | |
| SCHEMBL1997576 | 0.72 | GRM2 (0.60) | GRM2PPARGPPARDPPARA | |
| SCHEMBL1998223 | 0.72 | GRM2 (0.70) | GRM2 | |
| SCHEMBL1994458 | 0.70 | GRM2 (0.61) | GRM2PPARGPPARDPPARA | |
| SCHEMBL2001373 | 0.70 | GRM2 (0.71) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1855670-A2 | BENZAZOLE POTENTIATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Merck & Co., Inc. (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006091496-A2 | BENZAZOLE POTENTIATORS OF METABOTROPIC GLUTAMATE RECEPTORS | MERCK & CO., INC. (US) | 2006-08-31 | — | — | WO | disclosed |